The Otezla® (apremilast) Experience

The Otezla® (apremilast) Experience


My experience was positive. After a few
weeks, I noticed a change in my pain level and I was starting to feel better.
After a while, even my family began to notice. I was walking and moving around
easier, and after four months even began to gently exercise again. What was my
experience with Otezla? Otezla starts off in a titration program. Which means you
start on a lower dose, and then gradually increase it until you reach the dose
recommended by your doctor. The first few days on Otezla, I felt sick to my stomach.
But I really wanted to give this medication a shot, so I stuck with it.
After time, these side-effects went away. During the first couple of months taking
Otezla, I didn’t notice major changes in my symptoms. After more time had passed, I
suddenly realized my hands, wrists, and knees weren’t aching nearly as much as
before. Otezla® (apremilast) is a prescription
medicine approved for the treatment of patients with moderate to severe plaque
psoriasis for whom phototherapy or systemic therapy is appropriate.
Otezla is a prescription medicine approved for the treatment of adult
patients with active psoriatic arthritis. You must not take Otezla if you are
allergic to apremilast or to any of the ingredients in Otezla. Otezla can
cause severe diarrhea, nausea, and vomiting, especially within the first few
weeks of treatment. Use in elderly patients and the use of certain
medications with Otezla appears to increase the risk of having diarrhea,
nausea, or vomiting. Tell your doctor if any of these conditions occur. Otezla is
associated with an increase in depression. In clinical studies, some
patients reported depression, or suicidal behavior while taking Otezla. Some
patients stopped taking Otezla due to depression. Before starting Otezla, tell
your doctor if you have had feelings of depression, or suicidal thoughts or
behavior. Be sure to tell your doctor if any of these symptoms or other mood
changes develop or worsen during treatment with Otezla. Some patients
taking Otezla lost body weight. Your doctor should monitor your weight
regularly. If unexplained or significant weight
loss occurs, your doctor will decide if you should continue taking Otezla. Some
medicines may make Otezla less effective, and should not be taken with Otezla. Tell
your doctor about all the medicines you take, including prescription and
non-prescription medicines. Side effects of Otezla include diarrhea, nausea,
vomiting, upper respiratory tract infection, runny nose, sneezing, or
congestion, abdominal pain, tension headache, and headache. These are not all
the possible side effects with Otezla. Ask your doctor about other potential
side effects. Tell your doctor about any side effect that bothers you or does not
go away. Tell your doctor if you are pregnant, planning to become pregnant, or
planning to breastfeed. Otezla has not been studied in pregnant
women or in women who are breastfeeding. You are encouraged to report negative
side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch,
or call 1-800-332-1088. Please read the
Full Prescribing Information for Otezla.

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