Sodium and Autoimmune Disease: Rubbing Salt in the Wound?

Sodium and Autoimmune Disease: Rubbing Salt in the Wound?

millions suffer from asthma attacks triggered by exercise within five minutes of starting exercising people can get short of breath start coughing and wheezing such that lung function significantly drops but on a high salt diet the attack is even worse whereas on a low salt diet there’s hardly a significant drop in function at all to figure out why researchers had them all cough up sputum from their lungs and those on the high salt diet ended up with triple the inflammatory cells and up to double the concentration of inflammatory mediators but why what does salt intake have to do with inflammation we didn’t know until now the Western diet high in saturated fat and salt has long been postulated is one potential cause for the increasing incidence of autoimmune diseases in developed countries the rapidly increasing incidence of autoimmune diseases may be due to an over activation of immune cells called helper 17 cells the development of multiple sclerosis psoriasis type 1 diabetes Sjogren’s asthma and rheumatoid arthritis at all have all been shown to evolve this T helper 17 driven inflammation and one trigger for the activation of those th17 cells may be elevated levels of salt in our bloodstream the sodium content of processed foods and fast food can be more than a hundred times higher in comparison to similar homemade meals and sodium chloride salt appears to drive autoimmune disease by the induction of these disease-causing th17 cells turns out there’s a salt sensing enzyme responsible for triggering the formation of these th17 cells organ damage caused by high salt diet may also activate another type of inflammatory immune cell a high-salt diet can overwork the kidneys starving them of oxygen triggering inflammation the more salt they gave people the more activation of inflammatory monocytes cells associated with high salt intake induced kidney oxygen deficiency but this study only lasted two weeks what about long term one of the difficulties in doing sodium experiments is it’s hard to get free living folks to maintain a specific salt intake you can do what are called metabolic Ward studies or essentially lock people in a hospital ward for a few days and control their food intake but can’t do that long-term unless you can lock people in a space capsule Mars 520 was a 520 day space flight simulation to see how people might do on the way to Mars and back what they found was that those in a high-salt diet displayed a markedly higher number of monocytes which are a type of immune cell you often see increased in settings of chronic inflammation and autoimmune disorders this may reveal one of the consequences of excess salt consumption in our everyday lives since that so-called high salt intake may actually just be the average salt intake furthermore there was an increase in the levels of pro-inflammatory mediators in a decrease in the level of anti inflammatory mediators suggesting that a high-salt diet has the potential to bring about an excessive immune response which may damage the immune balance and result in either difficulties in getting rid of inflammation or even an increased risk of autoimmune disease what if you already have venado immune disease sodium intake is associated with increased disease activity in multiple sclerosis if you follow MS patients for a few years those eating more salt had three to four times the exacerbation rate three times more likely to develop new ms leash in their brains and on average had eight more brain lesions 14 in their brain compared to six in the low-salt group so the next step is to try treating patients with salt reduction and see if they get better but since reducing our salt intake is a healthy thing to do anyway I don’t see why anyone should have to wait [Music]


  • Patrick Bateman says:

    I am first.

  • Vegan Footsoldier says:

    Please clarify rice situation. Shitstorm has been unleashed.

  • Shelley Slatton says:

    I'm shocked!

  • Layinum2rest says:

    Dr. can you please make a video on how to improve gout symptoms please? thank you!

  • Eelke Aptroot says:

    Good thing I've been eating raw whole plant foods for the last 2 months…

  • Jigglypoop97 says:

    Is acne an autoimmune disease?

  • Gail Wautlet says:

    I wonder what it is about high sodium with alcohol together that makes such a deadly combination. I remember how drinking a salt rimmed glass of margaritas or eating salty pizza with beer made me look like a blow fish the next day. And why does one so often crave the other. Since going vegan I hardly ever get alcohol cravings.

  • whenstorm says:

    What kind of salt. NACL. sodium bicarbonate, all kinds of salt.

  • Masoud Abdun-Noor says:

    He never said that rice is bad in itself, he said that depending on where and how rice is grown it may have troubling amounts of arsenic. He said he has a slew of videos coming up about this, but until then just eat other whole grains like quinoa, etc

  • Potato Strong says:

    This is salt from a highly processed/animal based diet. The higher salt intake is in things like processed meats, cheese, processed foods. Were there any plant-based eaters eating sodium – no. We should be more clear and explain this in the videos. Salt is the scapegoat in many (most cases). See Dr. Pam Popper for more info.

  • Flash Man says:

    Dang paleo pushers keep saying that salt is important to drop your ph to battery acid level so your polypeptides can work to unwind protien to amino acids. They also keep saying salt is needed to activate the chief cells to produce more hydrochloric acids and that acid reflux is caused by the lack of salt! Paleo people are killing themselves

  • NGC6144 says:

    Is it really the salt or is it whatever baggage the salt is hitching a ride on?

  • dtadeo2006 says:

    Nice new presentation format Doc, NICE!

  • Rhyothemis princeps says:

    Thank you for this most excellent video!

  • Lichtblick says:

    Salt is in all sauces 🙁

  • Kerry Gorman says:

    A big thank you Dr. Greger!
    I have ms and am on a vegan low inflammation diet. I did not think sprinkling salt on my sweet potatoes had the potential to cause inflammation. Now I know better!

  • LL Lewis says:

    does he mean all salt or white table salt? I use pink and black salt

  • Flo T says:

    In a previous video about salt and heart health, Dr. Greger mentioned in that video a study done on vegans and people on SAD (Standard American Diet). The per diem recommended limit for sodium intake for those without heart problems was 2500mg. For those with heart problems, the limit was 1500mg. People on the SAD were consuming on average 3400mg of salt while vegans were hovering at about 1300-1400mg, being the only group to meet the recommendations. That being said, for people who are concerned about inflammation and autoimmune disease, the minimum necessary intake of sodium for proper body function is 180mg. A whole-foods plant-based diet can provide that amount of sodium as that amount is inherently found in fruits and particularly vegetables. No need to exacerbate things with added sodium, natural sodium in whole plant foods is best.

  • Nerds and Nutrition says:

    My father is currently in the hospital for severe pneumonia. He's also diabetic. They're feeding him overcooked vegetables, DIET ginger ale, and things like chicken parmesan. Exactly how are patients supposed to improve if their bodies aren't given the proper fuel?

  • Ronnie & Minh says:

    Eat raw and avoid all the bad stuff.

  • Pyriphlegeton says:

    The text animations look georgous and your video quality is generally amazing.
    However I would suggest not using the "page turning"-effect. I think it would look better and even more professional with a fast cut.
    I love your videos and however they are visually presented, I sincerely thank you for the valuable information. 🙂

  • TheOnlyFairee says:

    Good information! Not a fan of this editing style, though.

  • NICK COIN says:

    SUMAC can be used as a substitute for salt. It has somehow sour and salty flavor.The antioxidant value of Sumac Bran, Raw described in ORAC units is: 312,400 μ mol TE/100g.
    What is the most powerful superfood on earth? If you're basing your answer on which food has the highest concentration of antioxidants, then the answer is sumac bran. It doesn't get the buzz like acai or goji berries does, but the fact is that sumac has a higher ORAC value than any other food. In fact, it has over 3x the antioxidant content as acai and over 60x higher than blueberries.

  • Anna Fisher says:

    Is there a huge difference whether it is sea salt or iodized salt? I know cumin and celery make recipes more savory without the salt and you can always squeeze lemon or lime juice as well. Has Bragg's Liquid Amino proven a good alternative? Thanks so much for this video, I shared it as many of my friends and family deal with high blood pressure.

  • Aldi More says:

    This news about Sodium and autoimmune disease makes me wonder about my Celiac Disease being related to sodium intake. 25 years ago when I was diagnosed, I was on a steady diet of fast food, cola's and pizza. I also wonder if lowering my salt will help with my allergies. So many questions!!

  • Ana Patricia says:

    Thank you so much.
    And chicken nuggets and all junk food is just packed. Ugh!!!

  • Pony Chaser says:

    Dr. Greger is my only God!

  • yogiyoda says:

    I thought the healthy traditional Japanese diet was high in salt?

  • Keith Rowley says:

    Is this relevant for ulcerative colitis – another autoimmune disease?

  • Podi says:

    Interesting. I have noticed that I don't get as much exercise induced asthma as I used to, but I never connected it to salt intake, so it's really hard to tell whether that's been a major factor in the reduction, but it might well be. Unfortunately allergy induced asthma is going stronger than ever since I moved to where I live currently. I've already noticed a bit now that we've had spring weather for a few weeks and I'm not too excited for the summer, since the last two summers I needed my medication a lot just to get through the day.

  • Peter Rabitt says:

    As a lifelong asthma sufferer, I can confirm:
    A low sodium diet (<1,000 mg/day, and on top of a Greger-type diet) reduces my need for albuterol (asthma medicine) by 70%.

  • Scott S says:

    Nice work Doc

  • otis agabey says:

    As of 3/31/2017 Your website is asking for username and password at the entrance, what is that all about?

  • JustOneAsbesto says:

    This new video effect that highlights the relevant text and graphs from the scientific papers is greatly appreciated.

  • R.D. Dragon says:

    I've been trying to kick the salt and sugar habit for decades. People always say "cut back and you'll get used to it!" Well that has never happened yet. Food just doesn't taste good without salty and sweet flavors. It doesn't help that almost everything you buy in a package is full of salt and/or sugar. Some of us don't have the time, ability, and/or interest to spend hours preparing our own meals (on top of all the time researching what recipes are healthy and what balance of nutrients we need to put in our recipes).
    It's simply exhausting and it's no wonder most people just eat the food that's readily available and tastes good.

  • Delia says:

    This was so helpful Dr.G you have no idea! Thank you!!!

  • earthpet says:

    Two dietary things Americans fear most: animal product deprivation and salt deprivation. Giving up salt is MUCH easier than I thought it would be and it gets easier every day. But this is a change the VAST majority of Americans have no interest in undertaking. Those of us who do should get a discount on our insurance.

  • barzinio92 says:

    Dr. Greger and Dr. McDougall seem to deeply disagree on the subject. Damn! Which one to believe, I love them both!

  • Urban Assault Vegan says:

    Nice one

  • mjs1231 says:

    so what are safe levels of sodium per day. i have amys dinners for lunch. i usuualy have two a day. im wondering if im going over. suffer from imflammed sinuses for 4 years.

  • My channel It the worst by creating best work says:


  • An account says:

    Valuable info for autoimmune sufferers! Great that it's brought into attention. Though, I did cut out salt and nothing improved for my autoimmune condition. Makes me think…

  • Millenium Raymond Divine says:

    your term "high salt diet" used to describe a 'high salt diet' the studies reviewed is MISLEADING.. the studies don't take into effect what these patients are eating they could be eating the same inflammation-causing foods with varying salt amounts each producing high monocytes leukocytes and T helper 17 cells therefore the results are skewed and the studies need to be redone both with foods that are inflammatory and foods that are known to be anti-inflammatory as well as food combinations that are known to be anti-inflammatory also taking into account the various types of salt refined table salt versus Himalayan salt sea salt and other salt deposits with known mineral contents

  • Millenium Raymond Divine says:

    I appreciate you attempting to raise awareness however I ask that you post a disclaimer as to the studies reviewed or take the video down

  • Arkadius Bigotstrong says:

    I tried looking up the sources for an info about the diets on that low and high salt diet. Does anyone know what these diets were exactly ? How did they regulate what people in the study ate ?

  • Raziye Yıyın says:

    what is the presentation program?

  • susan brandt says:

    Wow, great info. Thanks!!

  • 07/16/14 says:

    This mske so much sense… Every time I eat a lot of salt I wake up the next day with a terrible case of gastritis. I need to stop. 😔

  • Jonathan Neal says:

    Would you change any of your nutritional advice for someone with an ileostomy?

  • Guersom Falcon says:

    Spanish translation is wrong ,please fix it

  • Thomas Moore says:

    Does anyone have an opinion on adrenal fatigue or does anyone have an opinion on adrenal fatigue or Addison's? I started adding sea salt to my food after feeling very fatigued and suffering with muscle cramps and I thought the sea salt was helping it certainly has made me have more energy.

    I don't eat any processed food with added salt and all the salt is added by me… it's less than a quarter of a teaspoon a day probably more like one eighth 8 or less.

    I've noticed my bowel movements improve as well… I'm going to try cutting down the salt or stopping it all together for a few days and see how it goes but I think it's been helping me..

  • ElChico114 says:

    its so funny that people think they know more than dr.greger. You guys only accept studies if they align with your lifestyle.

  • Dave p says:

    what about Himalayan salt? Is this more about iodized salt ?

  • 1operamom says:

    Wish they would state the measured amount of salt in those studies, rather than just low or high salt.

  • Libertad 1983 Bustinza says:

    How much salt can we eat every day?

  • Gary Brown says:

    It depends on the type of salt you eat
    All salt I'd not equal
    Its simple pink salt and sea salt are good for you
    Table or Morton is poisonous

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