New hope for treating multiple sclerosis

New hope for treating multiple sclerosis


(energetic music) – [Narrator] Doctor Benjamin
Segal came to U of M to head a new research and clinical center devoted to finding better ways
to treat multiple sclerosis. His studies are significant
because they suggest that people who present
the same clinical signs of multiple sclerosis may have two different forms of the disease. – Multiple sclerosis is driven by abnormal inflammation in
the brain and spinal cord. In the past it was taken for granted that the type of inflammation
that caused the damage was similar from one patient to another. However, our studies show
an identical clinical form of MS-like disease in animals could be caused by different
types of inflammatory molecules and white blood cells, and
this suggests that different treatments may be appropriate
for different individuals even if they appear similar clinically in terms of their symptoms. At the University of Michigan
the multiple sclerosis program has both a clinical
arm and a research arm. We do provide care and diagnostic services for patients with multiple
sclerosis and therapies. In addition, we have a
large research effort, and some of the work
that we’re doing is to develop blood tests that will allow us to improve diagnosis and
also to better monitor the disease state in patients
without doing MRI scans on a monthly basis for example. We are doing more studies in mice to better understand the
nature of the inflammation that causes the damage and to
investigate repair pathways in the central nervous system
that may hopefully one day allow us to develop
drugs that will reverse some of the deficits and symptoms that patients suffer from in this disease. Well, 15 years ago there
really weren’t any treatments that altered the history of patients with multiple sclerosis,
the clinical course. The only treatment we had were steroids which accelerated recovery from attacks but didn’t really alter longterm outcomes. Now there are five FDA
approved medications that decrease the risk of future attacks, future plaque formation in
the brain and spinal cord, and damage to nervous system tissues, and most experts in the field believe that our patients who
are on these treatments are doing much better than
patients have done in the past and are less likely to become
disabled as they get older. However, we still don’t have a cure. There’s a lot of progress
being made in terms of research and new strategies, and I’m
very optimistic for the future. (energetic music)

23 Comments

  • Jordan Dossett says:

    This was really good. It is nice to know that research is being done by others than just the pharmaceutical companies. I have MS and I know I often get very frustrated at the lack of information out there. It is really rough having a disease no one can see.

    ~ jordan
    (read my blog on ms and philosophy at 6hundred50thousand (.com) and see my art at jordandossett (.com)).

  • Randy Notfullname says:

    Stem Cell Therapy is being done in other countries successfully. Unfortunately, as an American doctor, you can't mention that here.

  • Randy Notfullname says:

    I am leaving on Jan 3 for Costa Rica to get Stem Cell Therapy at the Institute of Cellular Medicine. I have spoken to approximately 5 people who have had success with it (feel much better) although it is not a cure yet. It does cost of pretty penny. The $10,000 you spoke about is cheap. I'm paying $30,000. I'll let you know how it goes. I'll be there for 1 month.

  • kfoulk says:

    how did it go with the stem cells?

  • Paula Cooper says:

    How has stem cell research worked for anyone?

  • EssiacHempLaetrile says:

    imsucree …
    You Tube & Google "CCSVI"

    Google "pubmed" Enter words "Multiple Sclerosis Cannabinoids"

  • William Hammonds says:

    CCSVI and The Liberation Procedure!

  • Omar Dean says:

    CCSVI !!!!!!!!!!!!!!!!!!!!!!!!!

  • Steven Johnson says:

    I just started work on this ms problem, looking at work by others who came before me, and all roads lead me to the same place….. get this: smell (olfactory) and taste (gustatory)!!!! now what is that about???? it is all about the immune system— look into the work of these Doctors and see what I found….

  • Steven Johnson says:

    @migo53333

  • Barney Davis says:

    @largefolder1977 hey ..i am curiuos about the health of your neighbour now?

  • Dan Benn says:

    Of course, more drugs. That's where the money is. Why don't we do something useful and cure the disease instead of making the main goal reducing the effects of it. The MS Society is a sham. My family is involved with the societies board (not the very top, but high enough), and the MS Society (at minimum Canada) is fighting the CCSVI treatment all the way, and letting on they are all for it in the media. Behind the closed doors there is something very different going on, know that for fact.

  • worktosser says:

    @jessemac13 For me, weed exacerbates my MS – flattens me. Perhaps your claim that weed helps is more from a psychological one? No matter, it's not 'generically applicable' as a medicine for MS. I used to smoke weed.. I should know. lol.

  • csny19691 says:

    i agree with "UTELLMEGIRL" most Doctors who are researcing are only looking at numbers for their patients to be on a specific type of treatment so big pharmacy can make their money, no one at this point in time has found the answer for the cure. and yes i will agree stop thinking inside the box…then maybe we can have a solution.

  • jubilee203 says:

    Scientist discovered that All NON-Africans have bet. 1%-4% of Neanderthals DNA while 'pure' Africans(sub-saharan) don't have it. It seems like MS is very rare among 'pure' Africans compared to 60% of African Americans who have caucasian blood. I am just wondering if the Neanderthal DNA might have something to do with it. I guess there is an advantage to being 'pure' humans/homo sapiens/Africans with NO Neanderthal admixture. Question: is MS a Neanderthal disease?

  • Monika Polakowska says:

    In my opinion, I believe that there are different types/variations of all diseases i.e. different- and very specific- causes. Medication is a one-size-fits-all, and it assumes that what you have is the same thing as the next person. If you really want to get something treated, get educated and pin-point the treatments that have helped people who are similar to you i.e. have a similar lifestyle, diet or a similar group/severity of symptoms. You know your body better than anyone.

  • xzaxx says:

    people there is cure for ALS. it has been cure for this for the past 11 years. its outside of USA its only offered in costa rica. it is not alowed in USA or other countries.

  • onehundredvoices100 says:

    DR PAOLO ZAMBONI IN FERRARA ITALY TREATED HIS MS PATIENTS, FOR BLOCKED VEINS IN THE NECK & OR CHEST. THE MAJORITY OF THESE MS PATIENTS, SOME WITHIN HOURS, STARTED WALKING AGAIN. AS FOR FOLLOW UP STUDIES TO ZAMBONI'S TREATMENT (STENT TO OPEN VEINS THAT DRAIN THE BRAIN) WHY NOT ASK ZAMBONII'S FORMER MS PATIENTS, IF HIS TREATMENT WORKS. ——– DRINKING SODA POP WITH ARTIFICIAL SWEETENERS, CAN MIMIC, MS SYMPTOMS. LACK OF IODINE AND VITAMIN D, MAY CONTRIBUTE OR CAUSE, OTHER MS SYMPTOMS.

  • Remara Scottish says:

    @boxerpup7 are u sure i was getting worse with treatments tried 3 of them once i started i got relapses everymonth of 2010 when i stopped taking them relapses stopped but more stress and depression plz if u have any prove tell me im planning to take tysapri on wednesday plz

  • priya patel says:

    There is more hype about the CCSVI treatment now. It has helped so many MS patients around the world. There are certain clinic in the US who are participating in a clinical trial and following a certain protocol such as the one in Dayton, OH. They are providing treatment through the Hubbard Foundation and are approved by the NIH and IRB. Choosing the right clinic and radiologist is a hard decision and I just wanted to provide info for anyone seeking treatment. Hope this helps.
    daytonir.com

  • Dottie Hope says:

    In Dec 2011 we took our son 34 who has MS to a California CCSVI clinic ~~ he had the treatment and it is a year excatly since that treatment and there has been no improvement ~~ actually he is doing worse he also is on rebif injections ~~we are looking for other options ~~

  • SerbSimulator says:

    That was a very interesting post, Some of the natural cures for MS include…
    Get plenty of rest
    Exercising, yoga, tai chi, meditation, deep breathing, hypnosis,
    Use green juice, chlorella, fruit and veg – organic are best sunflower oils, evening primrose oil etc.
    Some things to avoid if you have ms are alcohol, chocolate, dairy products, eggs, commercially prepared and fast foods, margarine, milk, red meats, commercial salt, sugar, aspartame.
    (I discovered these and the reasons they work from Denelle Multi Care website )

  • pam lorenz says:

    Treating or curing???

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