Liver Failure | FAQ with Dr. Amy Kim

Liver Failure | FAQ with Dr. Amy Kim


(engaging music)>>When people say liver
failure it actually encompasses two different diseases. One would be an acute liver
failure and this happens in patients without any
underlying liver disease. For acute liver failure
symptoms can vary, but patients can present with nausea,
vomiting, extreme fatigue, or changes in their mental status, or feeling foggy in their head. Some people may present with jaundice and oftentimes with abdominal pain. And the second group would
be the chronic liver failure and this would be in
patients who actually have chronic liver disease or
end-stage liver disease, like cirrhosis and this would be more common than the acute liver failure. For our patients with
chronic liver failure, the symptoms would include jaundice, again the yellowing of the eyes and skin, fluids building up in their stomach, or having changes in their mental status like we mentioned earlier and sometimes even bleeding from the stomach. So the common causes of
acute liver failure include: acetaminophen toxicity,
or Tylenol overdose, and that’s followed by
any other drug-induced to liver injury, so these
are the most common causes of acute liver failure in the U.S. When you look at the world,
the top causes also include viral hepatitis, and most
commonly Hepatitis A, B, and E. For chronic liver disease
and end-stage liver disease it is more commonly in
patients with viral hepatitis such as Hepatitis B or C,
alcohol-induced liver injury would be another common risk factor to have end-stage liver disease. Some other causes also that
are rising and becoming very common would be a
non-alcoholic fatty liver disease that’s running in parallel
with obesity in the U.S. There are less common
causes including some genetic diseases such as
copper or iron overload, or auto-immune liver disease that can also contribute to end-stage
liver disease or cirrhosis. For a chronic liver failure
the only curative treatment that is available is
liver transplantation. So that’s why we focus a
lot on trying to pick up the disease early on
and to treat the disease before it becomes end-stage liver disease. For instance, for Hepatitis
C now that we have a curative treatment for Hepatitis C, we try to screen everyone who were born from 1945 to 1965, so they can actually be eligible to get Hep C treated. Same thing with non-alcoholic
fatty liver disease or alcohol-induced liver
disease, we try to detect this early so we can have
lifestyle preventions and try to prevent the
disease from progression. For acute liver failure
there are different drugs that people are testing
to see if we can improve the management of these
patients who are critically ill. For chronic liver disease
there’s a lot of focus in terms of understanding the mechanism of fibrosis, which is
the scarring of the liver that ends up with
cirrhosis, and to understand that process and once we
know that process more, I think there will be drugs
that be available for treatment. Also with the rising incidence
of non-alcoholic fatty liver disease, there’s a
lot of research focused on developing drugs to effectively treat non-alcoholic fatty liver disease. Once a patient has acute
or chronic liver failure the management really
involves multiple disciplinary team members, for instance
someone who was in the ICU with acute liver failure, the
patient would be co-managed by the intensivist as
well as the hepatologist, and also involve their
transplant surgeon as well to see the course of this illness
and how the patient is doing. For chronic liver disease,
or cirrhosis, as liver transplantation is one of
the main treatment options, there is a whole team
of liver transplantation team members who would
be managing the patients. This not only includes just
the medical hepatologist and transplant surgeons but
also includes: anesthesia, social work, psychiatry, and all of them are involved in the care of the patient. One of the fatal
complications of cirrhosis is also liver cancer, and
even with liver cancer is a multi-disciplinary
management where there is the hepatologist, the
hepatobiliary or transplant surgeon involved, as well as radiologists, that includes interventional radiologists, medical oncologists, and
radiation oncologists as well. So why at Hopkins we
have a multi-disciplinary liver cancer clinic,
where all the team members can discuss each case
together to figure out the best treatment plan for that patient, and this is the same
with our liver transplant evaluation clinic,
where a patient will see different specialty team members in their visit when
they come to our clinic. (engaging music)

26 Comments

  • Amu Celam says:

    Thank you sharing… ☺

  • Eddie Brown says:

    I have hep c… Stage 4.. Severe cirhossis.. An am taking hepc viral killers.. 2nd month.. Even if the meds cure the hep c.. I have stage 4 cirrhosis.. Do i need a transplant…. ?

  • 👉 CIick Here: Reverse Fatty Liver Disease Naturally! says:

    @Eddie Brown There is a solution and it's 100% natural

  • James Maturino says:

    I need know what kind insurance do have so i can be on waiting list so i can get a new liver

  • Lluvia Torres says:

    I have a fatty liver disease I would like to know what are the symptoms of fatty liver failure

  • ARIELCANADAGROUP COM Nitzavim Canada says:

    what the … I feel bad with my Liver I.have two emangiomas and NOW I was so stupid I took tylrenol

  • ALI EJAZ says:

    what is liver sickness and How to control complete guide

    https://sciencebiotechnology.com/what-is-liver-sickness-and-its-control-measures/

  • Michael Irwin says:

    This is the best YouTube video I've seen on this subject. Thank you. I experienced years of chronic Hep C that progressed to end-stage liver disease and liver cancer. I spent five years on the liver transplant list before receiving my transplant in 2016. I am indeed grateful and doing well. I was never one to try any alternative magical cures of any kind. Education, experience, and training ruled them out very quickly. My recommendation to anyone experiencing a diagnosis of liver disease is to do your due diligence on medical centers and doctors and then commit yourself to follow the protocols worked out for you by the team of hepatologists and be the best possible patient you can be. In addition, you will want to be sure to eat a healthy diet and exercise regularly. I switched to a vegetarian diet and rode my bike every day, even to frequent clinic visits and doctor appointments. It was a 35-mile round trip, which I made on average, four times each week. Best of luck to you and do take care of yourself.

  • znemyrkce II says:

    i knew there was something wrong with me lol

  • Astro Agena says:

    She is so swet 🙂

  • Marie Rabago says:

    Why do some hospital still give tylenol to a patient if a patient has liver problem

  • Valerie D says:

    Hello pls help us pass our subject in school by watching this 1 minute video: https://youtu.be/p1qdrEV31Bk

  • Katie G says:

    Can I just go ahead and put my name on the transplant list now? 😓 (j/k, I don’t deserve a healthy liver. 😑)

  • Jerred Morris says:

    When I was 29 my liver tried to shut down on me. I awoke in the hospital completely jaundiced, confused, nauseated, itchy, and in terrible pain. I was informed by the Dr's of my situation. I'd been going through Delerium Tremens for the first time ever. It was then that I was no longer able to hide my alcoholism. I should have died. I didn't deserve to stay no not me. But somebody above had a different opinion. I was barely living my life before. Always worried about my next drink. There is a better way people! I survived liver failure! Probably so that I can spread the experience, strength, and hope.

  • Throbbin So Hard says:

    she looks like a real life anime character

  • Hukam Singh Chouhan says:

    Very good video pls upload new video of alcohol effect on liver

  • Hukam Singh Chouhan says:

    Very good video pls upload new video of alcohol effect on liver

  • jeffroxx68 says:

    So much vocal fry

  • BigE3430 says:

    my dad was recently brought to the ER and we discovered that he has cirrhosis… I've been researching for good straight information on it. and this is the best video I've found. thank you for the direct straight answers

  • Angel Blue says:

    I was in my early thirties when a doctor mentioned my liver felt "hard". I am a recovering addict/alcoholic, and at the time my thing was Percocet. I did not know then that abuse of Tylenol in the Percocet would damage my liver. Hep C is a silent killer. In my forties, I graduated (: to the IV. Only did it for two years, but it was enough to catch Hep C. I found out I had it through a routine physical in my fifties after I got clean. I had NO symptoms whatsoever. Two more blood tests and a biopsy revealed that I had "stage two" damage, I caught it in time. People today getting treatment for this, you are very lucky. The first Hep C treatment was grueling. I had to inject myself in the stomach (thank God very, very thin needle, just a pinch) once a week with Pegylated Interferon and a huge horse pill for almost a year. The doctor told me to inject it on a Friday because I would need It destroys the good cells along with the bad, like chemotherapy. So, I had to inject two separate drugs once a weak on top of Interferon. Today, the treatment is just taking a pill for some time.

  • Rose Ault says:

    Glad I stopped drinking!!!

  • Aditya Gamer says:

    Medicine used liver 52 is it ok or not I feel nausea very much…….
    My hemoglobin leval is also low….

  • RebelWraith 81 says:

    Could acute liver failure mimic ulcerative colitis? My 12 year old son has been diagnosed with ulcerative colitis but prednisone and mesalamine aren't helping.

  • Methane Gummybear says:

    My aunt just died from this 🙁

  • Anu Karn says:

    I am from nepal. I am 51 years old. I am suffering from liver cirrhosis. My fibro scan report 74.8(kPa) CAP 312(dB/m) IQR 20 IQR2. 4 IQR/med 3percent. My latest hematology report Leucocyte count 3000 hemoglobin 12.32 platelets count 90000. INR 1.7 my LFT count bilirubin (total) 3.4 SGPT(ALT) 62. SGOT ( AST) 76.albumin 3.2 Alkaline phosphatase 341.My latest Altrasound report 1) MILD COARSE LIVER ECHO TEXTURE
    D/D CHRIS. LIVER PATHOLOGY
    2) SPLENOMENGALY
    3) LT. RENAL CORTICAL CYST.
    4) PROSTATOMGALY(23.5 Gm)
    ILBS Delhi Medicity Kathmandu diagnosed Liver cirrhosis but recent Altrasound report that there is no liver cirrhosis. Dr radiologist said there is no cirrhosis of liver. What can I do?? help me doctor ❤

  • Ahmad Ullah says:

    My brother is in stage 3 and he has cleared the hept c. Does he needs a liver transplant?

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